货号:AG-25A-0099B-C050 | 规格:50 ug | 目录价:¥3000 |
产品详情
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产品名称:
anti-Clusterin (human), pAb (Biotin)
别名:
TRPM-2; Apolipoprotein J; APO-J; CLI; CLU; SGP-2
产品描述:
Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80-kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.
宿主来源:
Rabbit
实验应用:
ELISA, WB
靶标/特异性:
Recognizes human clusterin. Detects a band of ~49kDa by Western blot.
免疫原:
Recombinant human clusterin (nuclear form).
偶联:
Biotin
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
有效期:
Stable for at least 6 months after receipt when stored at -20°C.
产地:
瑞士
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