EGFR CUTANA™ CUT&RUN Antibody-CUTANA™ CUT&RUN Antibodies-深圳欣博盛生物科技有限公司

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EGFR CUTANA™ CUT&RUN Antibody

品牌：EpiCypher

官网链接

说明书

折扣/货期

货号：13-2018

规格：100 µL

目录价：￥5985

产品详情

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产品名称:

EGFR CUTANA™ CUT&RUN Antibody

产品描述:

This antibody meets EpiCypher’s “CUTANA Compatible” criteria for performance in Cleavage Under Targets and Release Using Nuclease (CUT&RUN) and/or Cleavage Under Targets and Tagmentation (CUT&Tag) approaches to genomic mapping. Every lot of a CUTANA Compatible antibody is tested in the indicated approach using EpiCypher optimized protocols (epicypher.com/protocols) and determined to yield peaks that show a genomic distribution pattern consistent with reported function(s) of the target protein. EGFR is a tyrosine kinase receptor for epidermal growth factor (EGF) and other ligands of the EGF family. Activated EGFR can carry out its biological effects via the cytoplasmic pathway or nuclear pathway. The cytoplasmic pathway can cause tumorigenesis, metastasis, high proliferation, and resistance to chemotherapy and radiation.The nuclear pathway causes membrane EGFR to translocate into the nucleus and interact with other DNA-binding transcription factors, which can activate gene expression [1]. EGFR antibody produces CUT&RUN peaks above background (Figure 1) within gene promoters, intronic, and intergenic regions (Figures 1-2).

反应种属:

Human, Monkey (predicted)

宿主来源:

Rabbit

实验应用:

CUT&RUN, IHC, WB

免疫原:

Between amino acids 1100 and 1150

克隆性:

Polyclonal

保存温度:

Stable for 1 year at 4°C from date of receipt