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折扣/货期| 货号：200-23R-100UG | 规格：100 ug | 目录价：￥询价 |
| 货号：200-23R-10UG | 规格：10 ug | 目录价：￥询价 |
| 货号：200-23R-1MG | 规格：1 mg | 目录价：￥询价 |
| 货号：200-23R-250UG | 规格：250 ug | 目录价：￥询价 |
| 货号：200-23R-500UG | 规格：500 ug | 目录价：￥询价 |
| 货号：200-23R-50UG | 规格：50 ug | 目录价：￥询价 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Recombinant Human sIL-23 Receptor Fc
别名:
Interleukin-23 receptor
产品描述:
IL-23R is a 629 aa, novel subunit of the receptor for cytokine IL23A/IL23 which pairs with the receptor molecule IL12RB1/IL12R beta 1and thus take part in IL23A signaling. Signal transduction analysis confirms that this protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. Alternative splicing results in six spliced isoforms of IL-23R. Reports suggest that IL-23R plays an important role in psoriasis pathogenesis and is also a potential therapeutic target in inflammatory bowel disease. Recombinant Human IL-23 Receptor Fc is a 128.2 kDa homodimeric protein of 1128 amino acids, consisting of the extracellular domain of the mature sequence, as well as a 230-residue C-terminal Fc region linked by two glycines. As a result of glycosylation the Recombinant Human IL-23 Receptor Fc migrates to an apparent molecular weight slightly above 200 kDa by SDS-PAGE gel, under non-reducing conditions.
宿主来源:
CHO cells
保存温度:
Minus 20C
运输温度:
Room Temperature
预期分子量:
64.1
产品形式:
Bulk
产地:
美国
Accession #:
Q5VWK5
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