货号:V8877-100UG | 规格:100 ug | 目录价:¥6414.1 |
货号:V8877-20UG | 规格:20 ug | 目录价:¥2963.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
AMACR / p504S Antibody (Prostate Cancer Marker)
产品描述:
AMACR, also known as p504S, is an enzyme that is involved in bile acid biosynthesis and -oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB, IHC-P
同种型:
Rabbit IgG
免疫原:
A synthetic peptide from human AMACR protein was used as the immunogen for the AMACR antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Protein A affinity
保存温度:
Aliquot the AMACR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
产地:
美国
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