货号:AF-100-11-100UG | 规格:100 ug | 目录价:¥1477 |
货号:AF-100-11-1MG | 规格:1 mg | 目录价:¥4811 |
货号:AF-100-11-500UG | 规格:500 ug | 目录价:¥3216 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Animal-Free Recombinant Human IGF-I
别名:
Insulin-like Growth Factor-I, Somatamedin C, IGF-IA
产品描述:
The IGFs are mitogenic, polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar to insulin by structure and function, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant Human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds. The calculated molecular weight of Recombinant Human IGF-I is 7.6 kDa.
宿主来源:
E.coli
保存温度:
Minus 20C
运输温度:
Room Temperature
预期分子量:
7.6
产品形式:
Standard
产地:
美国
Accession #:
P05019
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