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折扣/货期| 货号：33184-1 mg | 规格：1 mg | 目录价：￥1204 |
| 货号：33184-10 mg | 规格：10 mg | 目录价：￥7042 |
| 货号：33184-25 mg | 规格：25 mg | 目录价：￥11732 |
| 货号：33184-5 mg | 规格：5 mg | 目录价：￥3836 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AZD 7986
别名:
Brensocatib|INS1007
产品描述:
An inhibitor of DPP-1 (IC50 = 3.9 nM); selective for DPP-1 over cathepsins S, -L, -B, -K, -D, -E, -Z, -H, and -G (IC50s = >20 µM for all), as well as a panel of >200 enzymes, receptors, ion channels, and transporters; inhibits activation of neutrophil elastase, proteinase 3, and cathepsin G in human bone marrow-derived CD34+ neutrophil progenitor cells (IC50s = 61.7, 208.9, and 114.8 nM, respectively); inhibits activation of neutrophil elastase and proteinase 3 in rat bone marrow lysates at 0.2, 2, and 20 mg/kg; suppresses NET formation, increases survival, and reduces the number of lung metastases in a 4T1 murine mammary carcinoma model
保存温度:
-20
运输温度:
-20
预期分子量:
420.46122
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
1802148-05-5
分子式:
C23H24N4O4
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