Clusterin Antibody / Apolipoprotein J / APO-J-单抗-深圳欣博盛生物科技有限公司

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Clusterin Antibody / Apolipoprotein J / APO-J

品牌：NSJ Bio

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说明书

折扣/货期

货号：V5842-100UG	规格：100 ug	目录价：￥6414.1
货号：V5842-20UG	规格：20 ug	目录价：￥2963.1

产品详情

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产品名称:

Clusterin Antibody / Apolipoprotein J / APO-J

产品描述:

Clusterin, also designated complement lysis inhibitor (CLI), apolipoprotein J (APOJ), sulfated glycoprotein 2 (SGP2), SP40 and testosterone-repressed prostate message 2 (TRPM2), is a secretory, heterodimeric glycoprotein that influences immune regulation, cell adhesion, transformation, lipid transportation, tissue remodeling, membrane recycling and cell-cell interactions. Clusterin is synthesized as a 449 amino acid polypeptide that is post-translationally cleaved at an internal bond between Arg 227 and Ser 228. Two subunits, ä¼ª and å°¾, are associated through disulfide bonds. The å°¾ subunit (also called ApoJä¼ª) corresponds to residues 23-227. The ä¼ª subunit (also called ApoJå°¾) corresponds to residues 228-449. Overexpression of Clusterin appears to be more common in late stages of mammary tumor progression. Clusterin markedly influences å°¾-Amyloid structure and neuritic toxicity in vivo and may influence Alzheimer s pathogenesis.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG2b, kappa

克隆性:

Monoclonal (mouse origin)

克隆号:

CLU/6692