Lovastatin-其他小分子化合物-深圳欣博盛生物科技有限公司

首页产品中心其他小分子化合物

Lovastatin

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CN2-0051-M005	规格：5 mg	目录价：￥240
货号：AG-CN2-0051-M025	规格：25 mg	目录价：￥600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Lovastatin

别名:

Mevilonin; MK-803; 6-alpha-Methylcompactin; BRN 3631989

产品描述:

Statin compound. Potent competitive HMG-CoA reductase inhibitor. Anti-hypercholesterolemic agent. Cholesterol/isoprenoid biosynthesis inhibitor. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. Inhibits the isoprenylation of Ras and Rho family GTPases . Anticancer compound that causes cell cycle arrest in G1 and G2/M phases through modulation of proteasome in cancer cell lines. SKP2 E3 ligase inhibitor. Decreases the expression of Skp2 and results in the inhibition of Skp2-mediated ubiquitination and degradation of p27 and p21, leading to cell cycle arrest and apoptosis. Smooth muscle cell proliferation inhibitor. Anti-adhesive, immunomodulatory and anti-inflammatory compound that stimulates bone formation. Suppresses TNF-induced NF-kappaB activation. Increases cellular resistance to anticancer agents such as doxorubicin and etoposide (Prod. No. AG-CR1-3572 http://www.adipogen.com/ag-cr1-3572/etoposide.html ). Suppresses ICAM-1-LFA-1 interactions, which blocks virus replication and infection. Anti-hypertensive agent. Modulates key cell signaling pathways, like Ras, MAPK and EGFR (modest). Lovastatin-treated neurons exhibit shortened neurite outgrowth.

宿主来源:

Synthetic.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

404.6

产品形式:

solid

有效期:

Stable for at least 2 years after receipt when stored at -20°C.