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折扣/货期| 货号：AG-45A-0043YEK-KI01 | 规格：96 wells | 目录价：￥7320 |
| 货号：AG-45A-0043YTP-KI01 | 规格：2 x 96 wells | 目录价：￥12840 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Progranulin (rat) ELISA Kit
别名:
Proepithelin; PEPI; PC Cell-derived Growth Factor
产品描述:
Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting-edge publications have shown that progranulin might be a biomarker not only for FTLD, but also for other types of Alzheimer‘s disease (AD). This new data even supposes the potential of progranulin to be a biomarker for MCI (Mild Cognitive Impairment), which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
靶标/特异性:
Detects rat progranulin. Does not cross-react with human progranulin.
保存温度:
+4°C
运输温度:
BI
有效期:
12 months after the day of manufacturing. See expiry date on ELISA Kit box.
产地:
瑞士
灵敏度:
40pg/ml
检测范围:
0.063 to 4ng/ml
检测方法:
Sandwich
样本类型:
Cell Culture Supernatant, Serum
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