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折扣/货期| 货号：SYN-1217-M001 | 规格：1 mg | 目录价：￥1204 |
| 货号：SYN-1217-M005 | 规格：5 mg | 目录价：￥2268 |
| 货号：SYN-1217-M010 | 规格：10 mg | 目录价：￥3780 |
| 货号：SYN-1217-M050 | 规格：50 mg | 目录价：￥询价 |
| 货号：SYN-1217-M100 | 规格：100 mg | 目录价：￥询价 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
S49076 HCl
别名:
S-49076 . HCl; (Z)-3-((3-((4-(Morpholinomethyl)-1H-pyrrol-2-yl)methylene)-2-oxoindolin-5-yl)methyl)thiazolidine-2,4-dione hydrochloride
产品描述:
S49076 is a novel, potent inhibitor of MET, AXL/MER and FGFR1/2/3. It can potently block cellular phosphorylation of MET, AXL and FGFRs and inhibit downstream signalling in vitro and in vivo. S49076 can inhibit the proliferation of MET- and FGFR2-dependent gastric cancer cells, block MET-driven migration of lung carcinoma cells, and inhibit colony formation of hepatocarcinoma cells expressing FGFR1/2 and AXL. S49076 has also been shown to cause tumour growth arrest in bevacizumab-resistant tumours in xenograft models.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
475
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95%
CAS号:
1265965-19-2
分子式:
C22H23ClN4O4S
溶解度:
Soluble in DMSO.
促销活动
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