货号:SBB-CE0011-C050 | 规格:50 ug | 目录价:¥4032 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Ubiquitin Activating Enzyme E1 [UBA1; UBE1] (human) (rec.) (untagged)
别名:
Ubiquitin E1 Enzyme; Ubiquitin-like Modifier-activating Enzyme 1; A1S9T; AMCX1; GXP1; POC20; SMAX2
产品描述:
UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer in its active state and catalyzes the first step of the ubiquitin conjugation cascade. It activates ubiquitin in an ATP-dependent mechanism where ATP is hydrolyzed to AMP and PPi, a ubiquitin C-terminal adenylate intermediate is formed, then transferred to the E1’s active site cysteine through a thioester bond. This thioester is then transferable to an E2 conjugating enzyme’s active site cysteine.
宿主来源:
Sf21 cells
产品浓度:
Lot dependent.
保存温度:
-80°C
运输温度:
Dry Ice
预期分子量:
~118kDa
产品形式:
liquid
存储溶液:
Liquid. In 50mM HEPES pH 7.5, 150mM sodium chloride, 10% glycerol, 2mM TCEP.
有效期:
Stable for at least 1 year after receipt when stored at -80°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
促销活动
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