货号:13-2026 | 规格:100 µL | 目录价:¥5985 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
EZH2 CUTANA™ CUT&RUN Antibody
产品描述:
This antibody meets EpiCypher’s “CUTANA Compatible” criteria for performance in Cleavage Under Targets and Release Using Nuclease (CUT&RUN) and/or Cleavage Under Targets and Tagmentation (CUT&Tag) approaches to genomic mapping. Every lot of a CUTANA Compatible antibody is tested in the indicated approach using EpiCypher optimized protocols (epicypher.com/protocols) and determined to yield peaks that show a genomic distribution pattern consistent with reported function(s) of the target protein. EZH2 catalyzes histone H3 lysine 27 trimethylation (H3K27me3), which leads to transcriptional repression of target genes [1]. EZH2 antibody produces CUT&RUN peaks above background primarily in intronic and intergenic regions (Figure 1) that overlap with H3K27me3 (Figure 2), consistent with its known role as the histone methyltransferase catalytic subunit of the Polycomb Repressive complex 2 (PRC2).
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
CUT&RUN, IP, WB
免疫原:
Between amino acids 696 and 746
克隆性:
Polyclonal
保存温度:
Stable for 1 year at 4°C from date of receipt
运输温度:
DO NOT FREEZE!! Frozen cold packs.
产品形式:
Antigen affinity-purified antibody in Tris-citrate/phosphate buffer pH 7-8, 0.09% sodium azide
产地:
美国
生产商:
EpiCypher
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