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折扣/货期| 货号：AG-CN2-0475-M001 | 规格：1 mg | 目录价：￥720 |
| 货号：AG-CN2-0475-M005 | 规格：5 mg | 目录价：￥2880 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Hellebrin
别名:
3beta-(O4-beta-D-Glucopyranosyl-alpha-L-rhamnopyranosyloxy)-5,14-dihydroxy-19-oxo-5beta,14-beta-bufa-20,22-dienolide; NSC93134
产品描述:
Highly potent Na+/K+-ATPase inhibitor, blocking the active efflux of Na+ and reuptake of K+. Water soluble cardiotonic glycoside from the class of bufadienolides (with 2-pyrone ring). Inhibits cancer cell growth in vitro. Shown to induce caspase-dependent apoptosis, reducing MDR resistance and the rate of mitochondrial oxidative phosphorylation in cancer cells. Inotropic by increasing the intracellular Ca2+ concentration. Immunosuppressive and anti-inflammatory agent that inhibits allogeneic T cell activation with much higher potency than cortisol or cyclosporin A. Anti-seizure activity in pentylenetetrazole (PTZ)-induced epileptical seizures.
宿主来源:
Isolated from Helleborus purpurascens.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
724.8
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>99% (HPLC and UV Absorbance)
CAS号:
13289-18-4
分子式:
C36H52O15
溶解度:
Soluble in water (~4mg/ml).
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