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折扣/货期| 货号：SIH-625-5MG | 规格：5 mg | 目录价：￥1108.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Safinamide
别名:
(S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide; FCE-26743; PNU-151774E; NW-1015
产品描述:
MAO-B Inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
302.3
产品形式:
White powder
产地:
加拿大
功能与背景:
A selective and reversible inhibitor of monoamine oxidase B (MAO-B, IC50=98 nM with greater than 100-fold selectivity over MAO-A) (1). It displays anticonvulsant activity (2) and protects against kainate-induced seizures and hippocampal neurodegeneration in rat models (3). Reduces overactive glutamatergic signaling via use-dependent sodium channel blockade (4). A novel therapeutic for Parkinson’s disease with multiple modes of action (5). Effective as an add-on to dopamine agonist therapy in early Parkinson’s Disease(6).
纯度:
>98% (HPLC); NMR (Conforms)
来源:
Synthetic
CAS号:
133865-89-1
分子式:
C17H19FN2O2
溶解度:
May be dissolved in DMSO (50 mg/ml)
PubChem CID:
131682
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