Myeloperoxidase Chlorination and Peroxidation Inhibitor Screening Assay Kit-抑制剂筛选试剂盒-深圳欣博盛生物科技有限公司

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Myeloperoxidase Chlorination and Peroxidation Inhibitor Screening Assay Kit

品牌：Cayman

官网链接

说明书

折扣/货期

货号：702930

规格：2 x 96 wells

目录价：￥5110

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Myeloperoxidase Chlorination and Peroxidation Inhibitor Screening Assay Kit

别名:

Myeloperoxidase

产品描述:

Cayman’s MPO Inhibitor Screening Assay Kit provides convenient fluorometric methods for screening inhibitors to both the chlorination and peroxidation activities of MPO. The chlorination assay utilizes a non-fluorescent thiomorphiline-based probe (NBD-TM), which is selectively cleaved by hypochlorite (-OCl) to yield the highly fluorescent compound, NBD.{71274} Fluorescence intensity is analyzed using an excitation wavelength of 500 nm and an emision wavelength of 550 nm. The peroxidation assay utilizes the peroxidase component of MPO, where a single two-electron oxidation of native enzyme (MPO) to compound I (MPO-I) is followed by two successive one-electron reductions back to native enzyme by compound II (MPO-II).{16905} The reaction between hydrogen peroxide and 10-acetyl-3,7-dihydroxyphenoxazine (ADHP) produces the highly fluorescent compound resorufin. Resorufin fluorescence is analyzed using an excitation wavelength of 530 nm and an emission wavelength of 590 nm.

保存温度:

-20

运输温度:

-20

有效期:

365

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