| 货号:AG-CN2-0024-M010 | 规格:10 mg | 目录价:¥360 |
| 货号:AG-CN2-0024-M050 | 规格:50 mg | 目录价:¥1080 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Piperlongumine
别名:
Piplartine; 5,6-Dihydro-1-(1-oxo-3-[3,4,5-trimethoxyphenyl]-trans-2-propenyl)-2[1H]-pyridinone
产品描述:
Cytotoxic against tumor cell lines [3, 4, 5]. Induces necrosis and apoptosis in cancer cells [5, 9, 12]. Shows anti-platelet aggregation activity possibly by inhibition of cyclooxgenase activity and a decrease in thromboxane A2 formation [4, 6, 10]. Shows significant anxiolytic and antidepressant activities [7]. Promotes adipogenesis of 3T3-L1 cells [8]. Induces in vivo and in vitro mutagenicity in eukaryotic models [11]. Selectively kills cancer cells by targeting the stress response to ROS [12]. Shows in vitro schistosomicidal activity [13]. Selective inhibitor of human immunoproteasome. Targets the beta5i subunit (LMP7) (IC50=15µM) with minimal inhibition of human constitutive proteasome [14].
宿主来源:
Isolated from Piper longum roots.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
317.3
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>97%
CAS号:
20069-09-4
分子式:
C17H19NO5
溶解度:
Soluble in DMSO, ethanol, methanol and dimethylformamide.
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