| 货号:AG-CN2-0025-C100 | 规格:100 ug | 目录价:¥300 |
| 货号:AG-CN2-0025-M001 | 规格:1 mg | 目录价:¥420 |
| 货号:AG-CN2-0025-M005 | 规格:5 mg | 目录价:¥840 |
| 货号:AG-CN2-0025-M025 | 规格:25 mg | 目录价:¥2160 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Rapamycin
别名:
Sirolimus; Rapamune; NSC 226080; Antibiotic AY-22989; WY-090217; RAPA; SILA 9268A; CCRIS 9024
产品描述:
Antibiotic. Antibacterial and antifungal properties [1, 2]. Forms a complex with FKBP12 and inhibits the mammalian target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells [3, 5, 6, 11]. Potent immunosuppressant [4, 10] used as an alternative to calcineurin inhibitors [12]. Restricts the proliferation of smooth-muscle cells by blocking cell cycle progression at the G1/S transition [7, 13]. Anti-proliferative. Antitumor compound [14, 15]. Apoptosis enhancer. Activator of autophagy both in vitro and in vivo [8, 9]. Anti-HIV and anti-aging compound [16, 17]. Neuroprotective [18]. Suppressor for self-renewal and vascular differentiation potential in hemangioma stem cells [19]. mTORC1 inhibitor [20].
宿主来源:
Isolated from Streptomyces hygroscopicus.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
914.2
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98%
CAS号:
53123-88-9
分子式:
C51H79NO13
溶解度:
Soluble in DMSO, methanol or chloroform.
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