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折扣/货期| 货号：SBB-PP0005-C050 | 规格：50 ug | 目录价：￥3248 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
20S Proteasome (human) (untagged)
产品描述:
The ubiquitin-proteasome pathway is the major proteolytic system in eukaryotic cells, where it catalyzes the selective degradation of short-lived regulatory proteins or the rapid turnover of misfolded proteins. One of the most important proteases in this pathway is the 26S proteasome, an ATP-dependent proteolytic complex, which is formed by the association of the barrel-shaped 20S proteasome (700kDa) and two 19S (700kDa) regulatory complexes. The 20S catalytic core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha-subunits and 2 rings are composed of 7 beta-subunits. The 20S catalytic core is able to degrade a variety of peptide substrates and poly-ubiquitinated proteins involved with apoptosis, DNA repair, endocytosis and cell cycle control.
宿主来源:
Human Erythrocytes
产品浓度:
Lot dependent.
保存温度:
-80°C
运输温度:
Dry Ice
预期分子量:
~700kDa
产品形式:
liquid
存储溶液:
Liquid. In 50mM HEPES pH 7.6, 100mM sodium chloride, 1mM DTT.
有效期:
Stable for at least 1 year after receipt when stored at -80°C.
纯度:
>95% (SDS-PAGE)
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