CYP2C9 Induction Reporter Assay Kit-细胞毒性检测-深圳欣博盛生物科技有限公司

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CYP2C9 Induction Reporter Assay Kit

品牌：Cayman

官网链接

说明书

折扣/货期

货号：601120

规格：100 tests

目录价：￥6496

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CYP2C9 Induction Reporter Assay Kit

产品描述:

Early screening of drug candidate’s potential to induce or inhibit CYP2C9 is a critical step in the drug development process. The CYP2C9 Induction Reporter Assay Kit is a novel method to evaluate CYP2C9 induction by drug candidates. Cayman's CYP2C9 Induction Reporter Assay Kit consists of a 96-well plate coated with a transfection complex containing a Secreted Alkaline Phosphatase (SEAP) reporter regulated by the human CYP2C9 gene promoter. Cells grown on the CYP2C9 Reporter Reverse Transfection Strip Plate will introduce the reporter gene and express GRα as well as HNF4α. Test compounds that promote binding of the nuclear receptors to the CYP2C9 promoter initiates SEAP expression. SEAP activity is subsequently measured using a luminescence readout. The kit is simple to use and can be easily adapted to high-throughput screening for potential nuclear receptor-mediated CYP2C9 inducers.

保存温度:

-20

运输温度:

-20

有效期:

365

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